The Goldhirsh Foundation's website is a brilliant example of pared-down design. There's no overcrowding or confusion on the homepage - just a simple (and clever) graphic explaining their values and mission to visitors.
Considering most website visitors navigate to the next page or website in seconds, using the prime real estate on your home page to communicate your organization's purpose like this is a smart move.
The rest of the site is also consistent with this theme - featuring clever and unique line graphics as a counterpoint to brief, concise copy. A great example of web design and copywriting.